FAQs
Which tissues can you process?
For germline testing, we recommend providing 1–2 ml of EDTA blood for optimal processing. However, we can also handle a variety of tissue samples, including buccal swabs and isolated DNA. If you have alternative materials, please reach out to us, and we would be happy to assist you. For optimal processing in somatic testing, we recommend providing an FFPE block or liquid biopsy samples collected in the appropriate biological sampling tube. Additionally, we can accommodate a variety of tissue samples, including cell blocks, cerebrospinal fluid, bronchoalveolar lavage, and isolated DNA or RNA. If you have alternative materials, please reach out to us, and we would be happy to assist you.
How can I send a sample to you?
VariantGen provides sample collection boxes upon request. These boxes are designed for transport and can be requested free of charge via mail or phone. Most samples can be shipped at room temperature from anywhere in the world.
How long does the test take?
Our turnaround time depends on the test. For prenatal cases, oncology cases or other medical urgencies (e.g., ICU patients), we prioritize the entire testing process. This expedited service is provided free of charge due to our full support for the better patient journey.
Can I speak with a medical doctor and expert from VariantGen before or after receiving my report if I have questions?
Yes, absolutely! We are here to support you with any questions you may have. This includes recommendations for the most appropriate genetic tests as well as assistance with interpreting the implications of our medical report.
What are chromosomes?
Chromosomes are structures that organize our DNA within cells. Humans have 46 chromosomes, with half coming from our mother and half from our father. On these chromosomes are genes, which contain instructions for making proteins. These proteins influence many of our traits and can also affect our risk for certain diseases.
What is DNA?
DNA, or deoxyribonucleic acid, is the genetic blueprint of life. It is a complex molecule found in every cell of our body, containing the essential instructions needed to create and maintain life. DNA serves as an information storage system, represented by a code composed of four letters corresponding to four nucleotides: adenine (A), thymine (T), guanine (G), and cytosine (C). The complete sequence of these nucleotides forms our genetic code, known as our genome. A single DNA molecule contains approximately 6 billion base pairs, and if you could unfold it, it would measure nearly 2 meters in length.
What is NGS?
NGS, or Next Generation Sequencing, refers to a set of advanced technologies that allow for the simultaneous sequencing of millions of DNA fragments. This parallel processing significantly improves response times and reduces the costs associated with genetic testing. Prior to the advent of NGS, sequencing an entire genome could cost millions of dollars. But thanks to the NGS, we can provide you the most reliable and cost-effective genetic testings in VariantGen.
What does it mean to have a genetic variant?
All individuals possess thousands of genetic variants in their DNA; however, having these variants does not necessarily mean that one will develop a genetic disease. Some variants contribute to our uniqueness, while others may slightly increase the likelihood of developing certain conditions. Additionally, some variants may require medical attention due to their potential health risks. It is important to interpret genetic reports in genetic consultation, that in VariantGen we help you to understand the implications of the information provided by the genetic tests.
Is it bad to be a carrier of a genetic mutation?
Being a carrier of a genetic mutation is not inherently negative. Every individual has variations in their DNA that contribute to their unique characteristics. Identifying these variations can be beneficial, as it allows for the establishment of guidelines and proactive measures to reduce the risk of developing related diseases. Early detection can also facilitate more effective treatment options if needed.
Why does the pricing for genetic tests vary so much?
The cost of genetic testing varies based on the technology used and the level of expertise needed to interpret the results. Generally, the more DNA and RNA information that is analyzed, the more reliable and clinically useful the results will be. At VariantGen, we use many different technologies for wide variety of tests, which examines all. Since this information can greatly influence diagnosis, treatment and future healthcare decisions, we believe it should be managed by a medical professional. We provide support for the entire process, working with your medical specialists and physicians to explain results and create an action plan to ensure you benefit fully from the information with our team in VariantGen.